Can I prep the components ahead of time?

Yes! You can prepare the seafood, Alfredo sauce, and lasagna noodles ahead of time. Store the components in separate airtight containers in the fridge for up to 2 days. Just assemble and bake when you're ready.

Do I need to pre-cook the noodles?

No, you do not need to pre-cook the noodles if you're using no-boil lasagna noodles. Just make sure they’re well-covered with sauce to soften as they bake. If you're using traditional noodles, you will need to pre-cook them before layering.

Can I make it gluten-free?

Absolutely! Simply substitute gluten-free lasagna noodles and ensure all other ingredients (such as the sauce and cheese) are gluten-free. You can easily make this dish gluten-free without compromising flavor.

What seafood can I include or substitute?

You can use a variety of seafood in this lasagna. Feel free to substitute the shrimp and crab with lobster, scallops, or other shellfish. You could even use white fish like cod or tilapia if you prefer.

Can I use jarred Alfredo sauce?

Yes, you can use jarred Alfredo sauce, but for a more authentic taste, I recommend enhancing it with a little extra cream, Parmesan cheese, or fresh herbs. Homemade Alfredo sauce will offer the richest flavor, though.

How should leftovers be stored and reheated?

Store leftovers in an airtight container in the fridge for up to 3 days. You can also freeze leftover lasagna for up to 3 months. To reheat, bake it in the oven or microwave, adding a bit of cream or sauce if needed to keep it creamy.

Seafood Lasagna with Shrimp & Crab – The Best Creamy Layered Dinner Recipe (2025) Tastyflora

Description

This creamy and flavorful Seafood Lasagna with Shrimp & Crab is layered with rich Alfredo sauce, tender noodles, fresh seafood, and melted cheeses. It’s the ultimate comfort food perfect for holidays, dinner parties, or any seafood lover’s dream meal.

Ingredients

Scale

Seafood Layer:

1 lb large shrimp, peeled and deveined
8 oz lump crab meat
1 tbsp olive oil
Salt & pepper to taste
1 tsp garlic powder

Alfredo Sauce:

4 tbsp unsalted butter
3 cloves garlic, minced
2 cups heavy cream
1 ½ cups grated Parmesan cheese
½ tsp Italian seasoning
Salt to taste

Other Layers:

9 lasagna noodles (boiled or no-boil)
2 cups shredded mozzarella cheese
½ cup grated Parmesan (for topping)
½ tsp crushed red pepper flakes (optional)
1 tbsp chopped parsley (for garnish)

Cook Mode Prevent your screen from going dark

Instructions

Cook the Shrimp & Crab
In a skillet, heat olive oil over medium heat. Sauté shrimp with garlic powder, salt, and pepper for 3–4 minutes until pink. Remove and set aside. Gently warm the crab meat just until heated through.
Make the Alfredo Sauce
In a saucepan, melt butter and sauté minced garlic until fragrant. Add heavy cream and bring to a simmer. Stir in Parmesan cheese and Italian seasoning. Cook until the sauce thickens slightly.
Boil the Noodles
If using regular noodles, cook according to package instructions. Drain and set aside with a light drizzle of olive oil to prevent sticking.
Assemble the Lasagna
In a 9×13″ baking dish, spread a layer of Alfredo sauce. Add noodles, seafood, cheese, and more sauce. Repeat layers, ending with sauce and mozzarella on top.
Bake
Cover with foil and bake at 375°F (190°C) for 25 minutes. Remove foil and bake another 10 minutes until cheese is golden and bubbling.
Garnish & Serve
Sprinkle with fresh parsley and red pepper flakes. Let rest for 10 minutes before slicing.

Notes

You can prep all ingredients a day in advance and store them separately in the fridge.
Add spinach or sautéed mushrooms between layers for extra flavor.

Use no-boil noodles to save time.

Prep Time: 25 minutes
Cook Time: 35 minutes
Category: Dinner, Main Dish
Method: Baking
Cuisine: Italian-American